Design Outside the Box—Jesse Schell
This is the amazing talk about the future of games that Jesse Schell gave at the 2010 DICE Summit. He talks not so much about what games will be like in the future, but about how gaming will leach out into every aspect of our lives. (February 2010)
UPDATE: There has been some interesting discussion around this video in recent days, from such luminaries as Dirk Knemeyer, Russell Davies, and Adam Greenfield. Fascinating stuff, and well worth a read.